Antiviral drugs earlier came in the 1980s with the objective of blocking HIV, the virus that motivates AIDS, from spreading in the body. They do not execute HIV, but they do support to avoid weakening of the immune system. That is why their use is integral for rising the life expectancy and condition of life of people with AIDS.The prevailing idea trailing present antiviral drug design is to analyzed viral proteins, or parts of proteins, that can be wrecked. These "targets" should be as unlike any proteins or parts of proteins in humans as possible, to cut down the possibility of side effects. The aim should also be common crosswise many strains of a virus, or even among diverse species of virus in the same family, so a single drug will have vast effectiveness.
CLASSES OF ANTIVIRAL DRUGS
Nucleoside Reverse Transcriptase Inhibitors – Act on the contrary transcriptase enzyme, assimilate themselves into the DNA conglomerate the virus creates. They discharge the chain and thus prohibit the virus from breeding itself. Drugs of this class include: Zidovudine, Abacavir, Didanosine, Stavudine, Lamivudine and Tenofovir.
Non-Nucleoside Reverse Transcriptase Inhibitors – Precisely block the operation of the enzyme and the amplification of the virus. Drugs in this class include: Efavirenz, Nevirapine and Etravirine.
Protease Inhibitors – Act on the protease enzyme, prevent its action and preventing the creation of new HIV infected cells. Drugs in this class include: Amprenavir, Atazanavir, Darunavir, Indinavir, Lopinavir/r, Nelfinavir, Ritonavir and Saquinavir.
Fusion inhibitors – Block HIV from arriving healthy CD4 cells, so therefore it cannot breed itself. Drugs in this class: Enfuvirtide.
Integrase Inhibitors – Prevents the activity of the integral enzyme, which consolidates HIV’s DNA into human DNA. In this way it inhibits the reproduction of the virus and its capacity to infect new cells. Drugs in this class: Raltegravir.
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