What Is GIST ?
Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal neoplasms of the gastrointestinal tract. GISTs emerges in the smooth muscle interstitial cell of Cajal. A gastrointestinal stromal tumor (GIST) is a type of tumor that occurs in the gastrointestinal tract, most commonly in the stomach or small intestine.
What Causes GIST?
The real cause of GIST is still unknown but an estimated 95% of patients with GIST have a protein called Kit that has grows and becomes abnormal, which later makes normal cells to grow faster and become cancerous.
Symptoms May Include:
- tummy (abdominal) discomfort or pain.
- blood in the stools (bowel motions) or vomit.
- anaemia (low level of red blood cells)
- a painless lump in the abdomen.
- being sick (vomiting)
- fatigue (tiredness and a feeling of weakness)
- a high temperature (fever) and sweating at night.
- weight loss.
How Is GIST Staged?
There is no definitive and precise staging system for GIST. However, the doctor will consider the size of the tumor, where it's located, whether it has spread, and how fast the tumor is dividing to determine how to treat the GIST and to help predict outcomes.
Gastrointestinal Stromal Tumor Risk Factors
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